While the injury bug hasn't really broken in the San Francisco 49ers' favor in 2025, that hasn't stopped Kyle Shanahan's squad from finding consistent success in the always challenging NFC West, going 8-4 through Week 12 thanks in no small part to their two-game win streak .

Unfortunately for the 49ers, their winning ways will be challenged in Week 13, when Brock Purdy and company will have to test their mettle against one of the best players in the game in Myles Garrett , who already has 18 sacks for the Cleveland Browns through just 11 games.

Asked how the 49ers can slow down one of the best players in the game in Shedeur Sanders' second professional start for Kevin Stefanski's squad, defensive coordinator Robert Saleh admitted he isn't sure , as even if the conditions may

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