Along with leftover turkey and sides, some people may still have wine left over after enjoying Thanksgiving dinner with friends and family. How long is it still good to drink?

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Wynn Roberton, the head sommelier at Bourbon Steak in D.C.’s Georgetown neighborhood, told WTOP that once you open a wine bottle, oxidation begins. Once oxygen enters the bottle, it can cause a flat taste, leading to a loss of flavor.

“The No. 1 killer of wine is oxygen,” he said.

Roberton, a Rockville, Maryland, native, said it is important to have a plan to protect the wine once you start pouring

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