Oklahoma Sooners quarterback John Mateer (10) leave the field after a win over the Missouri Tigers at Gaylord Family à Oklahoma Memorial Stadium in Norman, Oklahoma.

The LSU Tigers (7-4, 3-4 SEC) and Oklahoma Sooners (9-2, 5-2) tangle in Week 14 action Saturday in Norman, Oklahoma. The contest at Memorial Stadium will kick off at 3:30 p.m. ET (ABC). Let's analyze BetMGM Sportsbook's NCAA football odds around the LSU vs. Oklahoma odds and make our expert college football picks and predictions for the best bets.

Louisiana State heads to Norman after a lackluster effort in a non-conference game against a Group of Five opponent. The -24.5 Tigers yielded just 152 total yards to Western Kentucky, but edged the Hilltoppers in a 13-10 (Under 51.5) contest.

The No. 8 Sooners were a 4.5-point favorite when they defeated the then-No. 21 Missouri Tigers 17-6 (Under 42.5) last Saturday. Oklahoma won that battle in Columbia despite cranking out just 276 yards of total offense.

LSU defeated OU 37-17 last season in Baton Rouge and leads a 4-game all-time series 3-1.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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LSU at Oklahoma odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 8:55 p.m. ET.

  • Moneyline (ML): LSU +375 (bet $100 to win $375) | Oklahoma -500 (bet $500 to win $100)
  • Against the spread (ATS): LSU +10.5 (-105) | Oklahoma -10.5 (-115)
  • Over/Under (O/U): 36.5 (O: -105 | U: -115)

LSU at Oklahoma picks and predictions

Prediction

Oklahoma 24, LSU 10

Moneyline

No interest; PASS.

Against the spread

Since Oct. 18, LSU is 0-5 ATS and OU is 4-1 ATS. The Tigers are 1-5 ATS across their last 6 games on the road. Since 2020, the Sooners have gone 9-1 ATS in November home games.

From a down-to-down, success-rate standpoint, Oklahoma is at a clear advantage here. And most of that cushion comes on the defensive side of the ball. The Sooners are at top-10 success-rate levels against the run and the pass and are facing a Tigers offense that has managed just 19.0 points and 351.1 total yards per game since Sept. 27.

OU's front-7 havoc could well get intense, and LSU's offense as been awful in the red zone. That side of the ball may well translate into a 17-point advantage for Oklahoma.

On offense, the Sooners certainly haven't been great. But they have also been up against some very good defenses of late. Look for better passing results in this particular match-up.

Overall, OU's performances against the Auburn Tigers (24-17 on Sept. 20), Michigan Wolverines (24-13 on Sept. 6), Missouri and South Carolina Gamecocks (26-7 on Oct. 18) bode well as betting comps. The Sooners went 3-0-1 ATS across those 4 contests.

Revenge-minded OU is the play here. BACK OKLAHOMA -10.5 (-105).

Over/Under

OU games this season have gone 9-2 on the Under. The Under is 8-3 in LSU's 11 games. The Under is 6-1 across OU's last 7 home games.

LSU plays with a slowest-25 pace. Red-zone Tigers offense-vs.-Sooners defense figures to offer up few sixes. And rainy. windy weather is expected.

The UNDER 36.5 (-110) is the value side.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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This article originally appeared on Sportsbook Wire: LSU Tigers at Oklahoma Sooners odds, picks and predictions

Reporting by Skip Snow, Sportsbook Wire / Sportsbook Wire

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