Detroit Lions center Frank Ragnow failed his physical and will not play in 2025, per a team announcement.

Detroit’s medical team found a Grade 3 hamstring strain that will prevent Ragnow from completing his comeback attempt after retiring this offseason.

Head coach Dan Campbell said that Ragnow informed the team about the injury, prompting further evaluation.

That revealed a more severe injury that immediately eliminated the chance of Detroit’s longtime center playing this season.

Statement from the Detroit Lions pic.twitter.com/0qHJXzg35t — Detroit Lions (@Lions) November 29, 2025

Ragnow, 29, came out of retirement after the Lions suffered multiple injuries along their offensive li ne. Left guard Christian Mahogany broke his leg in Week 9 and could be out until the new year. C

See Full Page