Researchers at the Garvan Institute of Medical Research in Sydney, Australia, have discovered that an existing cancer drug may help treat the childhood cancer neuroblastoma , a cancer that that kills nine out of every 10 patients whose cancer recurs. The research, published in Science Advances , shows that an approved drug for lymphoma called romidepsin can induce cell death in neuroblastoma through pathways that remain active even when standard chemotherapy drugs lose effectiveness. The discovery may help clinicians design treatment combinations that can avoid the development of the resistance that makes relapsed neuroblastoma so difficult to treat.

“Finding a way to overcome the resistant state of relapsed high-risk neuroblastomas has been a major goal for my lab,” said senior

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