Amy Schumer has never shied away from speaking about her health journey over the years, particularly when it comes to her 40-lb weight loss transformation .

The comedienne candidly shared that her experience with GLP-1 medications, including Ozempic, Wegovy and Mounjaro, was not an easy one and came at a high price. GLP-1 medications work to suppress appetite, helping users lose weight, and are typically given to patients with diabetes.

© Instagram Amy has lost a reported 40 lbs during her weight loss journey

Her weight loss journey actually began back in 2022, when she underwent liposuction three years after the birth of her son, Gene, via C-section. Amy also had her appendix and uterus removed due to her endometriosis, and opted into the liposuction procedure as a result.

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