A groundbreaking study by researchers at the Indian Institute of Technology (IIT) Bombay and Monash University has revealed why tuberculosis bacteria manage to resist antibiotics. The study found that the bacteria alter the fatty outer layer of their cell wall, which aids in their resistance against current treatments.
This discovery shines new light on tuberculosis (TB), a disease that has plagued humans for over a century. In 2023, it was estimated that 10.8 million people contracted TB, while 1.25 million succumbed to it. With India bearing a large portion of the burden—over 2.6 million cases recorded in 2024—targeting the bacteria's outer membrane could be pivotal in combating the disease.
"Our research shows that focusing on weakening the bacteria's protective lipid membrane may enh

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