Researchers at the Health Research Institute Hospital La Fe (IIS La Fe) in Valencia, Spain, have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in urine could be a new and effective way to diagnose and stage bladder cancer . These findings, published in The Journal of Molecular Diagnostics , describe how the small fragment of the MYC gene, which is implicated in the development and progression of many types of cancer, could indicate the presence of both non–muscle-invasive and muscle-invasive bladder cancer.
“Our most significant finding was that the small fragment of the MYC gene may represent a valuable tool to diagnose bladder cancer, as it exhibited excellent specificity (97%) and predictive value (88%) for identifying muscle-invasive blad

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