A recent review concluded The PREVENT equations provide updated risk models for assessing cardiovascular disease risk. Studies comparing the Pooled Cohort Equation (PCE) and PREVENT consistently show lower atherosclerotic cardiovascular disease (ASCVD) 10-year risk estimates using the PREVENT equation, largely due to improved calibration of absolute risk levels. This shift has implications for the prescription of statin and anti-hypertensive medications, potentially leading to under-treatment and an increase in Major Adverse Cardiovascular Events (MACE), unless the risk thresholds for pharmacotherapy are lowered.

The authors advocated the selective use of non-invasive imaging, specifically Coronary Artery Calcium (CAC) scores, in conjunction with risk prediction equations to help guide th

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