AI-assisted summary

The Indianapolis Colts have lost three of their last four games and have not won in Jacksonville since 2014.

Running back Jonathan Taylor's performance has declined, and he faces a tough Jaguars defense that leads the league in rushing yards allowed.

Jacksonville quarterback Trevor Lawrence has been prone to interceptions and sacks, which could provide opportunities for the Colts' defense.

The Colts have to break a curse to take back control of the AFC South.

Indianapolis has lost three of its last four, allowed Jacksonville and Houston to come roaring back in the division race and faces the toughest December schedule of any team in the NFL.

Beginning with a place that has been so difficult for Indianapolis to win that it defies explanation. The Colts take on

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