Wilfried Nancy became the first Celtic manager to lose his opening two games as Roma won 3-0 at Parkhead.
Celtic were in disarray in the opening 45 minutes and trailed by three goals going into the break as Evan Ferguson netted twice to add to an early own goal from Republic of Ireland team-mate Liam Scales.
Arne Engels missed a penalty in first-half stoppage time before Celtic improved following a triple substitution at the break.
They could not make inroads on the scoreline as both sides had second-half goals disallowed for offside following VAR interventions.
The defeat leaves Celtic on seven points in the Europa League with two games remaining, away to Bologna and at home to Utrecht.
Just as Celtic have plenty of time to make up for Sunday’s home defeat by William Hill Premiership

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