TOPLINE:

Time to positivity, defined as the interval between blood culture incubation and the detection of pathogen growth, demonstrated a non-linear relationship with disease severity in bloodstream infections . Shorter times to positivity were associated with higher rates of 30-day mortality.

METHODOLOGY:

Researchers in Sweden conducted a population-based retrospective study to examine the association between the time to positivity and disease severity in bloodstream infections.

They sourced data from regional healthcare databases and included 12,585 bloodstream infection episodes.

Information on clinical characteristics, microbiological data, and prespecified disease severity markers (including laboratory values and vital signs) was also collected.

The primary outcome was 30-d

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