Route M, between Old U.S, 40 and County Road 240, is closed due to an overturned tractor trailer, according to the Missouri State Highway Patrol Troop F.

According to an X post , the tractor trailer is loaded with anhydrous ammonia, which is usually used as a type of fertilizer.

MSHP reports that there are currently no injuries or leaks at this time.

Drivers are being asked to avoid the area until the situation is cleared.

🚧 Route M Closed in Callaway Co. 🚧Route M, between Old US 40 and County Road 240, is closed for an overturned tractor trailer.The trailer is loaded with anhydrous ammonia. There are no injuries or leaks at this time. Please avoid the area and use an alternate route. pic.twitter.com/ZigSmUEtI0 — MSHP Troop F (@MSHPTrooperF) August 28, 2025

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