The Week 1 college football schedule has already seen some intriguing games on Thursday and Friday, but the action really ramps up beginning on Saturday with matchups that will shape the early College Football Playoff picture. Texas vs. Ohio State (-1), LSU vs. Clemson (-4) and Alabama vs. Florida State (+13.5) are among the huge matchups on Saturday, with more action coming on Sunday and Monday as well. Those college football spreads are all within a touchdown, but there are also some giants numbers on the Week 1 college football odds board as some teams are starting out with easier opponents.
The Week 1 college football spreads also list some potentially lopsided games like Michigan (-34.5) vs. New Mexico and Ole Miss (-34.5) vs. Georgia State. Making college football predictions for se