Week 1 of the 2025 college football season will conclude with a matchup between the North Carolina Tar Heels and the TCU Horned Frogs on Monday. This standalone matchup will finish off a five-day college football extravaganza to open the season, and there will be added attention as Bill Belichick makes his college football coaching debut. The Horned Frogs are favored by 3.5 points on the road in the latest North Carolina vs. TCU odds, while the over/under is 54.5, down four points from when the college football odds originally dropped. The Horned Frogs are -168 money line favorites, while the Tar Heels are +141 underdogs. Kickoff is scheduled for 8 p.m. ET at Kenan Stadium in Chapel Hill, N.C.

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