The southbound lanes of Interstate 75 are starting to reopen after a crash with injuries was reported near Wildwood.
Highway cams show significant backups at 3:30 p.m. Monday. Latest Forecast
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There was a complete road block at mile marker 329 in Sumter County.
The Sumter County Sheriff's Office said it was "a severe crash" and does not know how long the highway will be closed.
This is the third crash to shut down a highway on Monday in Central Florida.
>> This is a developing story and will be updated