A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain deterioration and disease.
FTL1 was brought to light through a careful comparison of the hippocampus part of the brain in mice of different ages. The hippocampus is involved in memory and learning, and it is one of the regions that suffers most from age-related decline.
The study team found that FLT1 was the one protein in this region that old mice had more of and young mice had less of.
The work was led by a team from the University of California, San Francisco (UCSF), and the researchers are hopeful that their findings will enlighten human treatments for neurodegenerative conditions, such a