Louisville football will be under the Friday night lights this week when it faces James Madison at L&N Stadium .

The Cardinals will have a short turnaround after a commanding 51-17 win over Eastern Kentucky to open the season. After leading 41-7 at halftime, U of L rested its starters, so the short week shouldn't affect them much. James Madison enters the Week 2 contest after defeating Weber State, 45-10, in its season opener.

Which team will be 2-0 after Friday night? Here's a look at our expert prediction. Buy Louisville vs. James Madison tickets

Louisville vs. James Madison prediction

Louisville and James Madison have played only once: The Cardinals won, 34-10, in 2022. Both squads have undergone significant changes since then. Louisville has a much deeper offense with three

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