The Week 2 college football schedule begins on Friday with four games, and continues into a Saturday full of mostly intriguing non-conference matchups. Perhaps the biggest is a top-20 showdown between Michigan and Oklahoma that features big-name quarterbacks. Five-star freshman Bryce Underwood gets his first big test for the Wolverines, while highly-touted transfer John Mateer leads the Sooners.

The latest Week 2 college football odds list the Sooners as 5.5-point favorites at home. Other Week 2 college football lines of note include Ole Miss (-10) vs. Kentucky, Oregon (-28.5) vs. Oklahoma State and Arizona State vs. Mississippi State (+6.5). Before locking in any Week 2 college football picks, be sure to see the top Week 2 college football expert picks, predictions and best bets from Th

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