The Week 2 college football schedule begins on Friday with four games, and continues into a Saturday full of mostly intriguing non-conference matchups. Perhaps the biggest is a top-20 showdown between Michigan and Oklahoma that features big-name quarterbacks. Five-star freshman Bryce Underwood gets his first big test for the Wolverines, while highly-touted transfer John Mateer leads the Sooners. This will be just the second-ever meeting between the programs, with OU winning in their 1976 Orange Bowl matchup.

The latest Week 2 college football odds list the Sooners as 5.5-point favorites at home. Other Week 2 college football lines of note include Ole Miss (-9.5) vs. Kentucky, Iowa vs. Iowa State (-3.5), NC State vs. Virginia (+3) and Illinois vs. Duke (+2.5). Before locking in any Week 2

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