Brant's best college football predictions and upset picks for Week 2 of the 2025 season. His top CFB underdogs and favorites on upset watch, including Ole Miss, more.

If you missed my upset watch column last week , you were probably shocked when Florida State walked over Alabama start-to-finish in Tallahassee last weekend. Then again, if you did read my column last week, you were definitely underwhelmed with Northwestern’s showing in New Orleans. It turns out I was wrong on Preston Stone elevating the Wildcats' offense. Hitting on two of my picks straight up and a third against the spread, it wasn't the worst Week 1 ever.

You can’t win them all, especially when the criteria is picking a multitude of underdogs. With that being said, I have identified a few Week 2 matchups that you s

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