Expert Week 1 NFL betting picks and analysis for Sunday's slate (2025). Get the best bets, point spreads, and for early and afternoon NFL games on 9/7/2025.

It's time to kick off the 2025 NFL season with my Week 1 best bets. You always want to approach the first week with caution, as it can be quite unpredictable. Just think back to last season, when the Cincinnati Bengals lost at home against Jacoby Brissett and the New England Patriots.

With that in mind, it's a good idea to tread lightly, building a smaller card, especially when the focus is on sharper markets like point spreads, totals, and moneylines, as it is on this page.

So, without further ado, let's dive into my Week 1 expert betting picks. Find out why I'm riding with the Arizona Cardinals, Cincinnati Bengals, Atlanta Falco

See Full Page