Sunday's Week 1 NFL schedule features a packed lineup of marquee matchups to kick off the 2025 season. Fans will see heavyweight clashes like the Steelers vs. Jets and divisional rivalry games like Seahawks vs. 49ers, Buccaneers vs. Falcons, Bengals vs. Browns, Giants vs. Commanders, and Lions vs. Packers. With such a loaded slate, daily Fantasy football players will need to dive deeper into NFL DFS player pool to find values for NFL DFS lineups. Should you target big name players like Ja'Marr Chase , Joe Burrow or Brock Bowers when making NFL DFS picks or building out you Week 1 NFL DFS strategy?

Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel , be sure to check out SportsLine's advanced NFL DFS Lineup Optimizer

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