In NFL Week 1, the Miami Dolphins travel to play against the Indianapolis Colts in an AFC tilt to start the season. The Dolphins finished second in the AFC East but had an 8-9 record in 2024. It was the same story for Indianapolis, which logged an 8-9 record as well and placed second in the AFC South. Miami owns a 48-29 all-time record over the Colts.

Kickoff from Lucas Oil Stadium is set for 1 p.m. ET on Sunday. Indianapolis is favored by 1.5 points in the latest Dolphins vs. Colts odds at bet365 Sportsbook, while the over/under for total points scored is 46.5. Before making any Dolphins vs. Colts picks or same-game parlays, be sure to see the Week 1 NFL predictions from SportsLine's proven model and check out the latest NFL odds . Bet on Dolphins vs. Colts at bet365, where you can g

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