Ukraine's Prime Minister, Yulia Svyrydenko, released a video message of her speaking from inside a government building in Kyiv which had been damaged by Russian strikes.

"I am now in a building of the Ukrainian government," she says.

"For the first time since the start of full-scale invasion, Russians struck our government headquarters in the center of Kyiv. You can see the consequences of the attack," she continues.

Svyrydenko also calls for assistance in closing Ukrainian skies to prevent further attacks and for more sanctions on Russia.

Russia hit Ukraine's capital with drone and missiles Sunday in the largest aerial attack on the country since the war began, killing at least two people and leaving smoke rising from the roof of a key government building.

Russia attacked Ukraine with 810 drones and decoys, Ukraine's Air Force said.

Yuriy Ihnat, a spokesperson for Ukraine’s Air Force, confirmed to The Associated Press that Sunday’s attack was the largest Russian drone strike since the full-scale invasion of Ukraine began. Russia also launched 13 missiles of various types.

Ukraine shot down and neutralized 747 drones and 4 missiles, according to a statement from the Air Force.

Hits from nine missiles and 54 drones were recorded at 33 locations across Ukraine, and the debris of shot down targets fell at eight locations, the Air Force said.

Associated Press reporters saw a plume of smoke rising from the roof of Kyiv’s cabinet of ministers building. It was not immediately clear if the smoke was the result of a direct hit or debris, which would mark an escalation in Russia’s air campaign, which has so far spared government buildings in the city center.

The building is the home of Ukraine's Cabinet, housing the offices of its ministers. Police blocked access to the building as fire trucks and ambulances arrived.