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Investigators seized approximately 500 pounds of methamphetamine from a San Jose home in a major drug bust.

Two suspects were arrested, while a third suspect escaped after a car chase and barricading themselves in a nearby home.

Authorities also seized a loaded handgun and about $4,000 in cash during the raid.

The operation was described as one of the largest methamphetamine seizures in Northern California in recent years.

Investigators seized roughly 500 pounds of methamphetamine from a San Jose home over the weekend in a bust they described as "one of the largest in Northern California in recent years."

Two suspects were arrested during the seizure, which resulted from a search warrant executed Saturday, Sept. 6, by deputies from the recently reestablished Sonom

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