Sep 7, 2025; Landover, Maryland, USA; Washington Commanders quarterback Jayden Daniels (5) looks to make a pass during the first quarter against the New York Giants at Northwest Stadium.

The 2025 "Thursday Night Football" schedule gets underway tonight to kick off Week 2 of the NFL season.

Divisional matchups make up the majority of the 16 games scheduled on Amazon Prime Video this season.

Of the 16 games Amazon Prime Video will stream this year, 10 of them are divisional games. Two divisions – the NFC North and AFC South – are not scheduled to have a divisional prime-time game on Thursday this year. It marks the second consecutive season the AFC South has been left without a divisional clash on "Thursday Night Football."

Week 8 and Week 12 will feature the only two interconference matchups of the year on "Thursday Night Football."

The prime-time action on Thursday nights began in 2006 with just five matchups. Now in 2025, "Thursday Night Football" reaches its 20th season of existence. Fan won't want to miss a second of the NFL action.

Here's the full "Thursday Night Football" schedule for the 2025 NFL season:

Catch "Thursday Night Football" all season with an Amazon Prime subscription

Thursday Night Football schedule 2025

All games are scheduled for 8:15 p.m. ET.

  • Week 2 (Sept. 11): Green Bay Packers vs. Washington Commanders
  • Week 3 (Sept. 18): Buffalo Bills vs. Miami Dolphins
  • Week 4 (Sept. 25): Arizona Cardinals vs. Seattle Seahawks
  • Week 5 (Oct. 2): Los Angeles Rams vs. San Francisco 49ers,
  • Week 6 (Oct. 9): New York Giants vs. Philadelphia Eagles
  • Week 7 (Oct. 16): Cincinnati Bengals vs. Pittsburgh Steelers
  • Week 8 (Oct. 23): Los Angeles Chargers vs. Minnesota Vikings
  • Week 9 (Oct. 30): Miami Dolphins vs. Baltimore Ravens
  • Week 10 (Nov. 6): Denver Broncos vs. Las Vegas Raiders
  • Week 11 (Nov. 13): New England Patriots vs. New York Jets
  • Week 12 (Nov. 20): Houston Texans vs. Buffalo Bills
  • Week 13 (Black Friday, Nov. 28): Philadelphia Eagles vs. Chicago Bears, 3 p.m. ET on Prime Video
  • Week 14 (Dec. 4): Detroit Lions vs. Dallas Cowboys*
  • Week 15 (Dec. 11): Tampa Bay Buccaneers vs. Atlanta Falcons*
  • Week 16 (Dec. 18): Seattle Seahawks vs. Los Angeles Rams*
  • Week 17 (Christmas Day, Dec. 25): Kansas City Chiefs vs. Denver Broncos

(*): Thursday games can be flexed up to twice between Weeks 14-16. Teams must be given a three-week notice before the game can be flexed.

Who plays Thursday Night Football Week 2?

The Washington Commanders will meet the Green Bay Packers at the historic Lambeau Field on "Thursday Night Football" in Week 2. The game will be exclusively available to stream on Amazon Prime Video.

This article originally appeared on USA TODAY: 'Thursday Night Football' schedule: NFL football prime-time schedule 2025

Reporting by Tom Viera, USA TODAY / USA TODAY

USA TODAY Network via Reuters Connect