The USC Trojans and Purdue Boilermakers will have their first meeting since 1998 this Saturday on CBS and Paramount+ . Both teams are kicking off their Big Ten schedules and will be facing fellow Power 4 teams for the first time this season. USC (2-0) has knocked off a pair of Group of Five programs, most recently defeating Georgia Southern, 59-20. Purdue (2-0) also prevailed over a Group of Five team in Week 1 before a triumph over FCS school, Southern Illinois, 34-17 in Week 2. USC is 3-1 all-time versus the Boilermakers.

Kickoff is at 3:30 p.m. ET from Ross-Ade Stadium in West Lafayette, Ind. The Trojans are 21-point favorites in the latest Purdue vs. USC odds, while the over/under for total points scored is 58.5. Before making any USC vs. Purdue picks, check out the college foo

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