The Purdue football team (2-0) faces off with USC (2-0) at Ross-Ade Stadium today.

Coming into the game, the Boilermakers are heavy underdogs, according to BetMGM . Will they pull off the upset at home in their Big Ten opener?

Follow along for live updates.

When is Purdue vs USC game in Week 3 of the college football season? What date is Purdue at Southern California football?

Purdue vs USC is Saturday, Sept. 13, 2025, at Ross-Ade Stadium in West Lafayette. Expert MLB daily picks: Unique MLB betting insights only at USA TODAY

What time does USC vs Purdue game start today, Saturday, Sept. 13, 2025? When does Purdue football vs USC begin?

Purdue vs USC begins at 3:30 p.m. ET Saturday, Sept. 13, 2025.

What channel is Purdue football vs USC game today? How to watch USC at

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