Andy's running back start 'em, sit 'em picks for fantasy football Week 2 lineups (2025). Read his expert RB start/sit advice for J.K. Dobbins, TreVeyon Henderson, Jaylen Warren, others.

In the opening week, fantasy managers saw several high-level running backs post mediocre performances. In addition, several fringe running backs made a strong claim to take over their backfield, one of which we will highlight in this piece.

Even though we are early in the season, it is essential to take all the data we have into consideration when building our lineups. Even if a player was viewed as the starter in the preseason, their role could change very quickly.

In this weekly piece, we don't look at those must-start options because if you have them, you start them. Instead, we look at those low-rang

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