The San Francisco 49ers (1-0) visit the New Orleans Saints (0-1) Sunday in Week 2. Kickoff from Caesars Superdome in New Orleans, Louisiana, is at 1 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Saints odds and make our expert NFL picks and predictions for the best bets.

The 49ers opened the season with a divisional road win, beating the Seattle Seahawks 17-13 Sept. 7. QB Brock Purdy threw 2 INTs but connected with third-string TE Jake Tonges for the game-winning touchdown with 1:34 left. Moments later, DE Nick Bosa sacked Seahawks QB Sam Darnold and forced a fumble with Seattle inside the 10 to seal the victory. Purdy and TE George Kittle were both injured in the game.

The Saints dropped their opener 20-13 at home to the Arizona C

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