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49ers vs. Jaguars tickets: How to buy, prices, game time for 2025 NFL Week 4 game in San Francisco

The Jacksonville Jaguars will be treated to some California heat when the Florida team faces the San Francisco 49ers on September 28.

Since 1999, both teams have faced off only seven times. The 49ers own a 5-2 record against the Jaguars, with the latter losing the last five matchups.

Can the 49ers overcome several obstacles heading into this Week 4 matchup? George Kittle has been out due to a hamstring injury, while quarterback Brock Purdy is dealing with a toe injury. Christian McCaffrey’s status will be in question following an

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