NEW ORLEANS -- Already without starting quarterback Brock Purdy and tight end George Kittle , the San Francisco 49ers will play the rest of Sunday's game against the New Orleans Saints without fullback Kyle Juszczyk .

Juszczyk suffered a concussion in the second quarter and was quickly ruled out for the rest of the game. It's unclear when or how Juszczyk suffered the concussion, but he spent more than five minutes in the blue medical tent before heading to San Francisco's locker room.

Kittle (hamstring) landed on injured reserve earlier this week while Purdy was ruled out on Friday because of toe and left shoulder injuries. Left tackle Trent Williams (knee) and receiver Jauan Jennings (shoulder) were listed as questionable after missing a couple of practice this week but bo

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