Key takeaways:

Recreational cannabis products with high concentrations of THC may be associated with worse mental health outcomes.

PCPs should ask patients about cannabis use in case it is impacting their mental health.

High-concentration THC products may be linked to poorer mental health outcomes, especially for some vulnerable populations, according to an expert.

Jonathan Samet, MD, MS, professor of epidemiology and of environmental and occupational health at Colorado School of Public Health, and colleagues recently conducted a systematic review that included 99 studies with 221,097 participants to examine associations between high-concentration THC and mental health outcomes. They published their findings in Annals of Internal Medicine.

At least 95% of the studies they evaluated

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