Kansas City Chiefs quarterback Patrick Mahomes scrambles during the Week 2 loss to the Philadelphia Eagles on Sunday. David Eulitt/Getty Images

The NFL season may be young, but the stakes are already high heading into Week 3. Joe Burrow is sidelined again, Patrick Mahomes is in uncharted territory, and a handful of teams are staring down the dreaded 0-3 start.

Here are five things you need to know.

Burrow sidelined again

Bad news in Cincinnati: Joe Burrow is out once again.

The Bengals quarterback – who was placed on injured reserved on Tuesday – suffered turf toe that requires surgery and is expected to miss at least three months, according to reports, derailing another season before it really gets going.

A trainer attends to Bengals quarterback Joe Burrow during the second qu

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