It’s amazing how a one-point loss on the road against a perceived inferior team can throw an entire season on its head. That’s kind of what happened with the Denver Broncos on Sunday, because now they have to try to take down the red-hot Los Angeles Chargers on the road in Week 3. Lose here and they are instantly two games back from the AFC West division lead. That’s the beginning of a long climb if it happens. It’s already a must-win situation for Denver.

Game Overview

Denver Broncos at Los Angles Chargers Sunday, September 21, 2025 at 2:05 P.M. Mile High time SoFi Stadium in Los Angeles, California ATS Betting Lines: Los Angeles -3 Moneyline Odds: Denver +130 / Los Angeles -154 Over/Under: 45.5 Note: All odds courtesy of FanDuel Sportsbook.

Collectively, our Mile High Report staff is

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