Is Joe Mixon out for the season? When is Joe Mixon coming back? The latest Joe Mixon injury update and fantasy football outlook heading into Week 4 of 2025.

Houston Texans running back Joe Mixon has yet to take the field this season as he has been dealing with a foot/ankle injury since the middle of July. However, the team has yet to provide any concrete update on his status, which is not a good sign for his long-term outlook.

With Mixon sidelined, Nick Chubb has taken the lead role, but rookie Woody Marks has begun to carve out a prominent role as the No. 2.

Will Mixon play again this season? Should fantasy managers stash him on their bench? Let's dive in! Be sure to check all of our fantasy football rankings for 2025:

2025 fantasy football rankings

Running back (RB) fantasy

See Full Page