The San Francisco 49ers' Week 3 victory against the Arizona Cardinals quickly turned into a bittersweet moment following the announcement that star edge rusher Nick Bosa will miss the remainder of the 2025 season after suffering a torn ACL. With the 49ers’ front office now tasked with finding his potential replacement and maximizing their undefeated start, focus is shifting to the trade market.

Tests today showed that 49ers Pro Bowl DE Nick Bosa suffered a season-ending torn ACL during Sunday’s win over Arizona, sources tell ESPN. It’s a clean tear, but Bosa now will need season-ending surgery. pic.twitter.com/f6xdHY0iVS — Adam Schefter (@AdamSchefter) September 22, 2025

Top-tier names such as Cincinnati Bengals defensive end Trey Hendrickson would provide the 49ers defens

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