Dangerous bacteria called carbapenemase-producing Enterobacterales (CRE), which can resist strong antibiotics, are spreading in the U.S., with a resistance type called New Delhi metallo-β-lactamase (NDM) that is becoming more common than the older type, Klebsiella pneumoniae carbapenemase (KPC), in E. coli, according to a new study published in Annals of Internal Medicine.
CRE are bacteria that normally live in the human and animal gut but can cause serious infections when they spread outside the digestive tract. This bacteria is resistant to carbapenems, which is a class of powerful antibiotics that are typically reserved as a last line of defense, according to study authors.
Resistance is driven by enzymes called carbapenemases, which break down these antibiotics. The type of carbape