Infections caused by a highly drug-resistant and dangerous bacteria known as NDM-producing carpabenem-resistant Enterobacterales, or NDM-CRE, have surged by more than 460% in the U.S. between 2019 and 2023, according to a CDC report.

NDM-CRE are resistant to some of the strongest antibiotics available, making them extremely difficult to treat, the agency said in a Sept. 23 report. These infections — including pneumonia, bloodstream infections, urinary tract infections and wound infections — are associated with high rates of morbidity and mortality. In 2020 alone, the bacteria caused an estimated 12,700 infections and 1,100 deaths in the U.S.

“This sharp rise in NDM-CRE means we face a growing threat that limits our ability to treat some of the most serious bacterial infections,” Danie

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