Perth grandmother Donna Nelson has lost her appeal to the Japan High Court against her drug smuggling conviction.

Nelson is serving six years' jail after two kilograms of methamphetamine were found in the lining of her bag at Tokyo's Narita Airport.

Nelson claimed she was the innocent victim of a love scammer and duped into carrying the bag that contained the drugs hidden in the travel case lining.

But a Japanese court ruled Nelson was negligent, and that she must have had doubts about what she was doing.

Nelson was involved in an online romance with a man called "Kelly", who claimed to have a fashion and travel case business in Japan.

The pair spoke for almost two years before he bought her tickets to Japan, with a three-day layover in Laos.

During this time, an associate of Kelly g

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