New provisional CDC data show U.S. cases of newborn syphilis increased for the 12th consecutive year in 2024, with nearly 4,000 cases reported. Newborn syphilis is a deadly but preventable consequence of the nation’s ongoing sexually transmitted infections (STI) epidemic.

In 2024, cases of newborn syphilis were:

Up nearly 2% over 2023, notably lower than double-digit increases that occurred in some recent years .

Up nearly 700% since 2015, when just 495 cases were reported.

The overall STI burden in the United States remains substantial, with more than 2.2 million cases reported in 2024, a 13% increase since 2015, according to these provisional data. However, there are encouraging signs of progress. In 2024:

Overall reported STIs declined 9% from 2023, down a third co

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