The Oregonian/OregonLive staff is back with its Week 5 college football predictions, highlighted by a massive clash between two top-10 titans: the undefeated No. 6 Oregon Ducks and the No. 3 Penn State Nittany Lions.

The Ducks will fly east for this first true test of the season, taking on an unbeaten Penn State squad in the electric atmosphere of a “White Out” game at Happy Valley. The prime-time contest is a highly anticipated rematch of last season’s Big Ten Championship, in which Oregon clinched the conference title.

The Oregon State Beavers will face another challenge as they host the undefeated Houston Cougars on a short week on Friday night. After a brutal opening stretch this season, the Beavers are desperate for a win.

Other matchups to watch include No. 4 LSU at No. 13 Mis

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