The Indianapolis Colts will attempt to stay undefeated on the season when they visit the Los Angeles Rams in Week 4 NFL action. Daniel Jones and the Colts (3-0) are one of three undefeated AFC teams following their decisive 41-20 victory against the Tennessee Titans in Week 3. They visit a Rams side (2-1) that is coming off a heart-breaking 33-26 loss to the Philadelphia Eagles.

Kickoff from SoFi Stadium is set for 4:05 p.m. ET. Los Angeles is a 3.5-point favorite in the latest Colts vs. Rams odds from SportsLine consensus, while the over/under for total points scored is 49.5. The Rams are -187 money line favorites (risk $187 to win $100), while the Colts are +156 underdogs. Before making any Rams vs. Colts picks, make sure you check out the picks from the SportsLine Projection Model.

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