Cincinnati Bengals wide receiver Ja'Marr Chase (1) reacts after making a catch against the Minnesota Vikings during the second half at U.S. Bank Stadium in Minneapolis, Minnesota.

The Cincinnati Bengals (2-1) and the Denver Broncos (1-2) meet in the second game of a Monday Night Football doubleheader at Empower Field at Mile High in Denver, Colorado. Kickoff is at 8:15 p.m. ET (ABC). Let's analyze BetMGM Sportsbook's Bengals vs. Broncos odds and tab the 5 best prop bets to win among SportsbookWire's expert NFL picks and predictions for Week 4.

The Bengals were crushed 48-10 at the Minnesota Vikings in Week 3 as a 3-point underdog as the Over (43) easily hit. QB Jake Browning struggled in his first start in place of Joe Burrow, managing just 140 yards with 1 TD and 2 picks. The Bengals’ rushing attack was no help either, finishing with only 53 yards.

The Broncos lost 23-20 to the LA Chargers on a last-second field goal. Denver pushed as a 3-point underdog as the Under (45.5) hit. RB J.K. Dobbins rushed for 83 yards and a TD, while WR Courtland Sutton broke out with 118 yards and a score. But 2 costly turnovers proved to be the difference.

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Bengals at Broncos prop bets

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:27 a.m. ET.

Broncos QB Bo Nix OVER 21.5 RUSHING YARDS (-110)

Cincinnati has struggled against athletic quarterbacks, and Nix has shown he’s willing to use his legs when needed. Through 3 games, he’s logged 71 yards on 19 carries (23.7 per game), and he’s cleared this number in back-to-back weeks — nearly doing it in Week 1 as well with 18 yards. His season-high 33 rushing yards came last week, and while he’s still searching for his first rushing TD of 2025, the usage is there. Against a defense that forces QBs to scramble and extend plays, I expect Nix to lean on his mobility enough to push past 20 yards.

Bengals WR Ja'Marr Chase OVER 5.5 RECEPTIONS (-120)

Chase is the Bengals’ clear No. 1 option and has proven quarterback-proof, even with Browning under center. In Week 3, Chase still led Cincinnati in targets, receptions, and yards, and through 3 games he’s averaging 7 catches per contest, right in line with his career average of 6.4.

Denver’s defense hasn’t allowed many explosive stat lines from wideouts, but volume is the key here. Browning leans heavily on Chase as a safety valve, and that usage alone makes this number too low. Chase doesn’t need a massive yardage total to cash this prop — he just needs steady involvement, and that’s one thing we can always count on.

  • BENGALS AT BRONCOS: Odds, picks, predictions

Bengals WR Tee Higgins UNDER 52.5 RECEIVING YARDS (-110)

Without Burrow, Cincinnati’s passing attack is severely limited, and Higgins has felt it. He’s cleared this number in just 1 of 3 games, and in Week 3’s blowout loss, he was a complete non-factor. Browning’s reluctance to push the ball downfield caps Higgins’ upside, as the Bengals’ offense has leaned more on short passes and check-downs.

The matchup doesn’t help either. Denver’s secondary has been tough, allowing just one receiver to top 80 yards all season. With defenses keying in on Chase and Higgins taking a backseat role in this offense, the opportunities simply won’t be there. Given Browning’s struggles under pressure, I’m confident the Under is the right side here.

Broncos QB Bo Nix OVER 1.5 PASSING TOUCHDOWNS (+105)

The rookie has had some ups and downs early, but his red-zone play has been improving, and even with a “slow start,” he’s still averaging 1.67 passing TDs per game. History also favors him at home, where he’s averaged 2.2 touchdown passes per game, compared to just 1.2 on the road.

This week’s matchup is favorable. The Bengals rank 26th in passing yards allowed and just made Carson Wentz look like his near-MVP self back in Week 3. Cincinnati has also given up multiple passing TDs in consecutive games, and Nix now gets them at home, where he’s been more comfortable. With plus odds attached, I see real value in backing Nix to clear this number.

Bengals QB Jake Browning OVER 0.5 INTERCEPTIONS (-185)

Browning looked overwhelmed in his Week 3 start, averaging just 5.2 yards per attempt while committing 2 turnovers. He was sacked 3 times and threw a pair of interceptions in Minnesota territory, including a first-quarter pick-six that immediately put Cincinnati behind.

The larger concern is that this isn’t a one-off. Browning has already thrown 5 INTs in 2 games this year, and in his extended run last season, he tossed 7 picks in 9 games. His inexperience shows under pressure, and Denver’s pass rush and secondary are built to exploit those kinds of mistakes.

Yes, the Broncos have only 1 interception so far this season, but this is a defense that produced 15 picks in 2024. Against a shaky quarterback on the road, I like their chances to add to that number. The odds are a bit steep, but this bet works perfectly as part of a Single Game Parlay (SGP).

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This article originally appeared on Sportsbook Wire: Cincinnati Bengals at Denver Broncos best prop bets for Monday Night Football

Reporting by Drew Phelps, Sportsbook Wire / Sportsbook Wire

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