On Sunday afternoon, the San Francisco 49ers suffered their first defeat of the 2025 NFL season with a narrow home loss to the Jacksonville Jaguars. The game marked the return of previously injured quarterback Brock Purdy , who had a mixed bag of an afternoon on Sunday, throwing for 309 yards and two touchdowns, but also tossing a couple of interceptions.

Purdy had missed the previous two games with a toe injury and was replaced by Mac Jones, and after Sunday's game, those issues reportedly flared up again .

“QB Brock Purdy came in ‘complaining of some soreness in his toe' today, according to Kyle Shanahan. Purdy and Shanahan talked on the phone last night. Purdy said he had no issues during the game,” reported Nick Wagoner of ESPN on X, formerly Twitter.

Further complicating matt

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