Midtown’s tallest-ever skyscraper , to be anchored by Ken Griffin’s financial companies, has gotten the green light in a 48-0 vote by the City Council — a rare unanimous endorsement by the often development-averse body.

The plan for a new 350 Park Ave. represents a remarkable personal commitment by mega-billionaire Griffin, who’s a partner with two major development companies — privately held Rudin and publicly traded Vornado Realty Trust.

The 1,600-foot-tall tower will dwarf Midtown’s current cloudbuster king, the JPMorgan Chase headquarters at 270 Park Ave. , by 200 feet. Its 1.7 million square feet of floor space will be anchored by two Griffin-owned companies, Citadel and Citadel Securities, which will occupy 850,000 square feet. 4

Demolition of three buildings now at the si

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