NFL Week 5 kicks off with the San Francisco 49ers vs, the Los Angeles Rams on Thursday, October 2 (10/2/2025) in a can’t miss clash between two 3-1 postseason contenders. Later in the weekend, the final two undefeated teams put their records on the line as the Eagles host the Broncos and the Bills host the Patriots on Sunday, October 5.

NFL Week 5 games air in-market on a variety of channels, including NBC, CBS, FOX, ABC, NFL Network and ESPN. Fans can stream coverage live on fuboTV (free trial) . Non-cable games stream live on Prime Video .

NFL Week 5 schedule

Games on CBS and FOX are in-market only. If you are out of market, you can add NFL RedZone on fuboTV and Sling, NFL Sunday Ticket on DirecTV, or subscribe to NFL Plus , to still enjoy out-of-market NFL action on

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