AI-assisted summary

The San Francisco 49ers will face the Los Angeles Rams in a Week 5 matchup.

Kickoff is scheduled for 8:15 p.m. on Thursday, Oct. 2, 2025, at SoFi Stadium.

Both the 49ers and the Rams enter the game with identical 3-1 records.

The game will be broadcast on Prime and can be streamed on NFL+.

The 2025 NFL season continues with the San Francisco 49ers traveling to SoFi Stadium to take on the Los Angeles Rams on Thursday.

Here's what you need to know about how to watch the Rams vs. the 49ers , tonight's matchup , the NFL Week 5 schedule , TV lineup and more. 2025 NFL season record AI predictions: Win-loss picks for all 32 teams

What time does Los Angeles Rams - San Francisco 49ers game start on Thursday Night Football tonight, Oct. 2, 2025? Wh

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