The Los Angeles Rams are coming off of a 27-21 over the Indianapolis Colts on Sunday, and now they’ll take on the San Francisco 49ers for a Thursday night NFC West battle at SoFi Stadium.

Los Angeles played arguably their best game of the season against the Colts, as their offense was strong, and their defense forced some turnovers. San Francisco lost in Week 4, falling to the Jacksonville Jaguars despite getting quarterback Brock Purdy back for the matchup.

There will be plenty of eyes on the Rams in this game for NFL purposes, but they also have multiple fantasy-relevant players who are in consideration to start in most leagues. As Los Angeles prepares for their fifth game of the year, let’s look at what fantasy owners should do with their Rams in Week 5.

QB Matthew Stafford: Start

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